Vayne

Best duos with Vayne

ADC Tier B49.5% WR

Vayne is played as ADC. Tank-shredding marksman with percent true damage. Duels and scales like few others. Below are the 2 champions it pairs best with according to real match data — the duos that raise Vayne's win rate the most.

Best synergy partners

ADC · 1

Ashe AsheADCBetween Ashe's control and Vayne's pressure, targets rarely get away.

Support · 1

Milio MilioSupportMilio's crowd control locks enemies in place just long enough for Vayne to deal damage safely.
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Frequently asked questions

Who synergizes best with Vayne?

Vayne's strongest duo partners right now are Ashe, Milio — they raise Vayne's win rate the most based on real match data.

What is the best duo for Vayne?

Ashe (ADC) is currently the highest-synergy partner for Vayne.