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Best duos with Vayne
Vayne is played as ADC. Tank-shredding marksman with percent true damage. Duels and scales like few others. Below are the 1 champions it pairs best with according to real match data — the duos that raise Vayne's win rate the most.
Best synergy partners
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Frequently asked questions
Who synergizes best with Vayne?
Vayne's strongest duo partners right now are Lulu — they raise Vayne's win rate the most based on real match data.
What is the best duo for Vayne?
Lulu (Support) is currently the highest-synergy partner for Vayne.