Vayne

Best duos with Vayne

ADC Tier B49.9% WR

Vayne is played as ADC. Tank-shredding marksman with percent true damage. Duels and scales like few others. Below are the 7 champions it pairs best with according to real match data — the duos that raise Vayne's win rate the most.

Best synergy partners

Top · 1

Mordekaiser MordekaiserTopMordekaiser brings the initiation: it engages first and Vayne turns that control into damage.

Jungle · 1

Lee Sin Lee SinJungleLee Sin brings the initiation: it engages first and Vayne turns that control into damage.

Mid · 1

Sylas SylasMidSylas chips enemies down from range and sets up the fights Vayne closes out.

Support · 4

Nami NamiSupportNami's crowd control locks enemies in place just long enough for Vayne to deal damage safely. Milio MilioSupportMilio's crowd control locks enemies in place just long enough for Vayne to deal damage safely. Thresh ThreshSupportWith hard engage, Thresh opens fights and pins targets so Vayne can capitalize. Nautilus NautilusSupportWith hard engage, Nautilus opens fights and pins targets so Vayne can capitalize.
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Frequently asked questions

Who synergizes best with Vayne?

Vayne's strongest duo partners right now are Nami, Milio, Thresh — they raise Vayne's win rate the most based on real match data.

What is the best duo for Vayne?

Nami (Support) is currently the highest-synergy partner for Vayne.